- Product Details
Keywords
- Pramipexole
- Pramipexole Powder
- Pramipexole for Parkinson Disease Treatment
Quick Details
- ProName: Pramipexole Pharmaceutical Raw Powder ...
- CasNo: 191217-81-9
- Appearance: white powder
- Application: Dopamine Agonist
- DeliveryTime: within a week
- PackAge: Discreet packing ways as your requirem...
- Port: shenzhen hongkong
- ProductionCapacity: Metric Ton/Day
- Purity: 99%
- Storage: Store in cool and dry area and keep aw...
- Transportation: DHL EMS AND SO ON
- LimitNum: 0 Metric Ton
Superiority
Rich experience.
We have specialized in this field for 7 years. Our steroids and hormones have been exported to overseas, like Europe, Africa, Asia, America and other countries. And we have got very good feedback from our customers, and established long friendly relations of cooperation.
High quality products with the best price
1.All powders are factory directly supplying and have much in stock.
2.Before each powder send out, it all will be tested again by our technician, if the quality good, then it can be sent out to customers.
Professtional packing and fast delivery
1.Professtional team for packing, different country and quantity order have different packing way, sure package the products the best to your order.
2.We have mass stock, so that we can guarantee all the package can be sent out as soon as possible after you pay and should arrive your hands 3-7 days safely by DHL,TNT,FEDEX,HKEMS,UPS,etc.
Best pre-sell and after-sell service.
1.Once the package send out, tracking number and packing picture should email you later
2.For raw powder buyer, we also can help you cook steroid powder into injection and supply you all the things to make ready use injection, such as 10ml vials,0.22um-0.45um whatman filter,crimper machine and filter pump.
Customer feedback
Hi , package delivery and packed well , very satisfed with your service,wish cooperation with you again
—— Jason Davis
I am very very appreciate with the product quality , high purity and good appearance. wish you good business
—— Larry Owe
although some problems happens on the purchase , you show me a good attitude to resolve it and I got the product , good job
—— Terry Neal
Order Process :
1. |
We talk with the order and total cost |
2. |
Client sends money and supply ship infomation |
3. |
We send package and supply track number |
4. |
Package delivery and after sold service |
Details
Pramipexole Pharmaceutical Raw Powder for Parkinson Disease Treatment
1. Pramipexole is a dopamine agonist belonging to the same class of drugs as Cabergoline. The primary purpose of this drug is in the treatment of Parkinson's disease.
2. Pramipexole is most commonly found under the brand names Sifrol, Mirapexin and Mirapex, although generics are also available. Mirapex is the most well known brand by Boehringer Ingelheim Pharmaceuticals.
3. Along with treating Parkinson's, Pramipexole is also prescribed for the treatment of restless legs syndrome. The drug has also shown promising signs in the treatment of bipolar depression, although it has never officially held this label.
4. Pramipexole is a non-ergoline dopamine agonist indicated for treating early-stage Parkinson's disease (PD) and restless legs syndrome (RLS).It is also sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants.
5. Pramipexole has shown robust effects on pilot studies in a placebo-controlled proof of concept study in bipolar disorder. It is also being investigated for the treatment of clinical depression and fibromyalgia.
Application:
1. Pramipexole is a dopamine agonist that directly correlates with the prolactin hormone. As dopamine levels in the body go up, prolactin levels go down. It does this by having a direct effect on the dopamine D3 receptor. Although it also acts on the D2 receptor its affinity for the D3 receptor is seven times greater than any existing dopamine agonist.
2. The effect of Pramipexole on the D3 receptor has a strong impact on the neurological system, which is why it's used to treat Parkinson's disease and in some cases Alzheimer's disease. Through acting on the D3 receptor, Pramipexole also affects a man's sexual interest and activity.
3. Prolactin is in part directly responsible for a man's refractory period, which refers to the time it takes to recover from sexual activity so that performance can occur again. By lowering prolactin through an increase in dopamine, Pramipexole can directly reduce the refractory period resulting in the ability to perform sexually more frequently.
Usage:
1. To alleviate the symptoms of Parkinson's disease: Parkinson's disease is due to the movement of brain dopaminergic neuron loss caused by dopamine deficiency, lead to patients with tremor, rigidity and bradykinesia and a series of symptoms.
2. Hydrochloric acid highly selective effects on dopamine D2 and D3 receptor agonist, dopamine release, improve motor symptoms. Research on Shannon display, early Parkinson's disease patients pramipexole monotherapy after, can effectively control the motor symptoms in patients with early stage, to help maintain the ability of daily life.
3. Pramipexole in combination with levodopa can effectively improve the ADL score and motor symptoms in patients with advanced Parkinson's disease score in patients with advanced Parkinson's disease, make life more vibrant.