Founded in 2011 Wuhan Godbullraw Chemical Co., ltd. is a modern advanced enterprise specializing in custom synthesis and R&D and exportation of APIs, peptides, Sarms, Local anesthetics, plant extract etc. We build cooperation with labs and factory qualified with GMP, DMF, FDA in China and world wild. We take advantage of integrating factory resources and lab customized projects. For customer demand, we continue to expand the industry chain in familiar areas, and at the same time we also keep developing new product supply chain. We have 7 synthesis labs, 3 scale-up labs and 3 analysis labs. Our factory covers a total area of 13500 square meters, and we have highly educated and experienced chemists. We have strong supply system and purity raw. As the shipping, we cooperate with 10 experienced shipping companies to make sure ETA by a safe delivery to the worldwide.

We will choose the best shipping for you and according to your order amount. Our products are almost entirely safe delivery without custom risk and we promise you will get packs after payment. If the package is lost, we will reissue it. Our company has been established for 12 years and has a complete industrial chain. In the past three years, we have lost only one parcel. If this happens, please contact us and we will reissue it to you immediately.

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Product name:Pramipexole powder
Other name:mirapex   
CAS:191217-81-9 
Appearcance: white Pramipexole powder
MF:C10H21Cl2N3OS
MW:302.26
Pramipexole powder Specification: 98.5% HPLC
Usage:Pramipexole powder is A dopamine-D2-receptor agonist. Antiparkinsonian

1. Pramipexole is a dopamine agonist belonging to the same class of drugs as Cabergoline. The primary purpose of this drug is in the treatment of Parkinson's disease.

2. Pramipexole is most commonly found under the brand names Sifrol, Mirapexin and Mirapex, although generics are also available. Mirapex is the most well known brand by Boehringer Ingelheim Pharmaceuticals.

3. Along with treating Parkinson's, Pramipexole is also prescribed for the treatment of restless legs syndrome. The drug has also shown promising signs in the treatment of bipolar depression, although it has never officially held this label.

4. Pramipexole is a non-ergoline dopamine agonist indicated for treating early-stage Parkinson's disease (PD) and restless legs syndrome (RLS).It is also sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants.

5. Pramipexole has shown robust effects on pilot studies in a placebo-controlled proof of concept study in bipolar disorder. It is also being investigated for the treatment of clinical depression and fibromyalgia.

Application:

1. Pramipexole is a dopamine agonist that directly correlates with the prolactin hormone. As dopamine levels in the body go up, prolactin levels go down. It does this by having a direct effect on the dopamine D3 receptor. Although it also acts on the D2 receptor its affinity for the D3 receptor is seven times greater than any existing dopamine agonist.

2. The effect of Pramipexole on the D3 receptor has a strong impact on the neurological system, which is why it's used to treat Parkinson's disease and in some cases Alzheimer's disease. Through acting on the D3 receptor, Pramipexole also affects a man's sexual interest and activity. 

3. Prolactin is in part directly responsible for a man's refractory period, which refers to the time it takes to recover from sexual activity so that performance can occur again. By lowering prolactin through an increase in dopamine, Pramipexole can directly reduce the refractory period resulting in the ability to perform sexually more frequently.

Usage:

1. To alleviate the symptoms of Parkinson's disease: Parkinson's disease is due to the movement of brain dopaminergic neuron loss caused by dopamine deficiency, lead to patients with tremor, rigidity and bradykinesia and a series of symptoms.

2. Hydrochloric acid highly selective effects on dopamine D2 and D3 receptor agonist, dopamine release, improve motor symptoms. Research on Shannon display, early Parkinson's disease patients pramipexole monotherapy after, can effectively control the motor symptoms in patients with early stage, to help maintain the ability of daily life.

3. Pramipexole in combination with levodopa can effectively improve the ADL score and motor symptoms in patients with advanced Parkinson's disease score in patients with advanced Parkinson's disease, make life more vibrant.
 

FAQ:

Q1: Do you offer free sample
A: Of course, we will offer free sample if you pay shipping fees.

Q2: How to solve the quality problem
A: We supply high quality products and quality issue near to zero. If it happens caused by occasional case, we will reship again or compensate customer loss, but customer need show us the evidence of problems or test report.

Q3: Whether transportation is safe and whether to reship if seized
A: Yes, we offer almost 100% Shipping line with safe delivery. If seized unfortunately, we will ship and I am sure no custom issue.

Q4: ETA
A: Pack sent out in 2-3 days and offer tracking numbers after payment. ETA not the same decide by destination country. Please contact us for details (always 10-15 days).

Q5: Do you have any discount
A: The price is negotiable. Plz shoot us your order content, we will quote a fair price.

Q6: What is your minimum order
A: Usually MOQ is 100g. But depends on the items and your requirements, we also can support small quantity, such as 20g and 50g.

Q7: How to order
A: E-mail or message us that includes your order like format below:
product A   100g
product B   10vials
delivery country: 
Our sales will quote a total cost includes shipping fees and each item fees in 12 hours regularly. 
Our will satisfy your purchase and supply professional guide.