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Product Name: Decapeptide-12

 

CAS No.: 501-30-4

 

Formula: C65H90N18O17

 

Purity: >98%

 

Solubility: souble in water

 

Appearance: white powder

 

Decapeptide-12 reversibly binds to tyrosinase, an enzyme found in a number of different pigment-producing cells. It prevents tyrosinase from catalyzing the oxidation of phenols, the first step in melanin production. In mammals, tyrosinase is found only in melanosomes, special compartments within pigment-producing cells.

 

Tyrosinase is not preserved across species and, in fact, can differ drastically in structure even among closely-related species. In humans, differences in the efficiency of tyrosinase determine skin color and are the result of slight modifications in the TYR gene found on chromosome 11 .

 

 Decapeptide-12 is approximately 17 times more potent than previous treatments for hyperpigmentation, including hydroquinone . Studies in cultured melanocytes over 7 days demonstrated a 27%-43% reduction in melanin content .

 

Decapeptide-12 has undergone multiple animal trials and may eventually be included in commercial products for treating hyperpigmentation.