Founded in 2011 Wuhan Godbullraw Chemical Co., ltd. is a modern advanced enterprise specializing in custom synthesis and R&D and exportation of APIs, peptides, Sarms, Local anesthetics, plant extract etc. We build cooperation with labs and factory qualified with GMP, DMF, FDA in China and world wild. We take advantage of integrating factory resources and lab customized projects. For customer demand, we continue to expand the industry chain in familiar areas, and at the same time we also keep developing new product supply chain. We have 7 synthesis labs, 3 scale-up labs and 3 analysis labs. Our factory covers a total area of 13500 square meters, and we have highly educated and experienced chemists. We have strong supply system and purity raw. As the shipping, we cooperate with 10 experienced shipping companies to make sure ETA by a safe delivery to the worldwide.

We will choose the best shipping for you and according to your order amount. Our products are almost entirely safe delivery without custom risk and we promise you will get packs after payment. If the package is lost, we will reissue it. Our company has been established for 12 years and has a complete industrial chain. In the past three years, we have lost only one parcel. If this happens, please contact us and we will reissue it to you immediately.

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Name:PRL-8-53 HCl
Chemical name:Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate
Synonyms:PRL-8053;PRL-8-53;Methyl 3-(2-(benzyl(Methyl)aMino)ethyl)benzoate hydrochloride;3-(2-Benzyl(methyl)aminoethyl)benzoic acid methyl ester hydrochloride;m-[2-(Benzylmethylamino)ethyl]benzoic acid methyl ester hydrochloride;Benzoic acid, 3-(2-(Methyl(phenylMethyl)aMino)ethyl)-, Methyl ester, hydrochloride
CAS 51352-87-5
MF:C18H22ClNO2
MW 319.82578
Dosage:Subjects in human trials have been given up to 100 mg a day and did not appear to develop any negative side effects.
 
PRL-8-53 HCL Description:
PRL-8-53 (chemical name Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate) is a synthetic nootropic compound discovered in 1972 and patented in 1975 by the late Dr. Nikolaus Hansl, a neuropharmacologist at Creighton University in Omaha, Nebraska. Preliminary animal tests indicated that the compound was both safe and significantly nootropic, boosting avoidance learning in rodents with no adverse effects. But the real interest in PRL-8-53 was sparked by a 1978 study on human volunteers, which showed that a single dose of the compound could improve word retention scores by more than 200%.

How Does NSI-189 works
PRL-8-53's exact mechanisms of action are not well understood, but it is generally believed to regulate the brain's production of and response to several crucial neurotransmitters. In his reports on human and animal studies Hansl indicated that PRL-8-53 potentiates dopamine, partially restricts production of serotonin, and enhances the brain's response to acetylcholine.
Though Hansl's research report on the 1978 human study suggests those actions, it does not clearly delineate the mechanism of action.The fact that older subjects saw the most nootropic benefit from taking the drug supports the concept that dopamine modulation plays a major role in PLR-8-53's effects. Up-regulating the normal age-related lessening of dopamine production that is associated with cognitive decline could have a significant positive impact on both learning and memory.

PRL-8-53 HCL Dosage :
The only human study on PRL-8-53 was based on the ingestion of a single 5 mg dose. There is no data on the effectiveness or potential toxicity of any other dosage in humans.

FAQ:

Q1: Do you offer free sample
A: Of course, we will offer free sample if you pay shipping fees.

Q2: How to solve the quality problem
A: We supply high quality products and quality issue near to zero. If it happens caused by occasional case, we will reship again or compensate customer loss, but customer need show us the evidence of problems or test report.

Q3: Whether transportation is safe and whether to reship if seized
A: Yes, we offer almost 100% Shipping line with safe delivery. If seized unfortunately, we will ship and I am sure no custom issue.

Q4: ETA
A: Pack sent out in 2-3 days and offer tracking numbers after payment. ETA not the same decide by destination country. Please contact us for details (always 10-15 days).

Q5: Do you have any discount
A: The price is negotiable. Plz shoot us your order content, we will quote a fair price.

Q6: What is your minimum order
A: Usually MOQ is 100g. But depends on the items and your requirements, we also can support small quantity, such as 20g and 50g.

Q7: How to order
A: E-mail or message us that includes your order like format below:
product A   100g
product B   10vials
delivery country: 
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